Cattle vaccination has potential benefits to reduce prevalence, incidence and spread of bTB in the cattle population. Vaccination could help prevent breakdowns by preventing herds becoming infected by any source - wildlife or cattle and could also reduce the severity of a herd breakdown. Vaccination that is less than 100% effective will not guarantee all cattle are fully protected from infection and therefore vaccination alone cannot be used to define disease free status. Lead vaccine candidate in the short to medium term is BCG.

Link: http://www.defra.gov.uk/foodfarm/farmanimal/diseases/atoz/tb/documents/vaccine_cattle.pdf